Please Note:

The Open Access Repository has moved to a new authentication system as of the 1st of November.

Account holders will now be able to login using their University of Tasmania credentials.
If you have trouble logging in please email us on E.Prints@utas.edu.au so we can assist you.

Public users can still access the records in this repository as normal

Open Access Repository

MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis

Downloads

Downloads per month over past year

Dombrecht, B and Manners, JM and Kazan, K and Xue, GP and Sprague, SJ and Kirkegaard, JA and Ross, JJ and Reid, JB and Fitt, GP and Sewelam, N and Schenk, PM (2007) MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis. The Plant Cell, 19. pp. 2225-2245. ISSN 1040-4651

[img] PDF
4289.pdf | Request a copy
Full text restricted

Abstract

The Arabidopsis thaliana basic helix-loop-helix Leu zipper transcription factor (TF) MYC2/JIN1 differentially regulates jasmonate (JA)-responsive pathogen defense (e.g., PDF1.2) and wound response (e.g., VSP) genes. In this study, genome-wide transcriptional profiling of wild type and mutant myc2/jin1 plants followed by functional analyses has revealed new roles for MYC2 in the modulation of diverse JA functions. We found that MYC2 negatively regulates Trp and Trp-derived secondary metabolism such as indole glucosinolate biosynthesis during JA signaling. Furthermore, MYC2 positively regulates JA-mediated resistance to insect pests, such as Helicoverpa armigera, and tolerance to oxidative stress, possibly via enhanced ascorbate redox cycling and flavonoid biosynthesis. Analyses of MYC2 cis binding elements and expression of MYC2-regulated genes in T-DNA insertion lines of a subset of MYC2–regulated TFs suggested that MYC2 might modulate JA responses via differential regulation of an intermediate spectrum of TFs with activating or repressing roles in JA signaling. MYC2 also negatively regulates its own expression, and this may be one of the mechanisms used in fine-tuning JA signaling. Overall, these results provide new insights into the function of MYC2 and the transcriptional coordination of the JA signaling pathway.

Item Type: Article
Journal or Publication Title: The Plant Cell
Publisher: American Society of Plant Biologists
Page Range: pp. 2225-2245
ISSN: 1040-4651
Identification Number - DOI: 10.1105/tpc.106.048017
Date Deposited: 07 Apr 2008 14:31
Last Modified: 18 Nov 2014 03:35
Item Statistics: View statistics for this item

Actions (login required)

Item Control Page Item Control Page
TOP