Open Access Repository
Accuracy and clinical utility of the CoaguChek XS portable international normalised ratio monitor in a pilot study of warfarin home-monitoring
Downloads
Downloads per month over past year
![]() |
PDF
4347.pdf | Request a copy Full text restricted |
Abstract
Aim: To evaluate the accuracy of the CoaguChek XS international normalised ratio (INR) monitor
compared to the laboratory method.
Methods: The accuracy and ease of use of the recently marketed CoaguChek XS portable INR
monitor was evaluated in 17 patients involved in a trial of warfarin home-monitoring. INR results from
the monitor were compared to the laboratory method. Clinical applicability was measured by
discrepant INR values, defined in the literature by expanded and narrow agreement criteria, and by the
proportion of INR values differing by more than 15% and 20% from the laboratory method.
Results: Participants provided 59 comparison INR measurements for analysis. The paired results were
highly correlated (r = 0.91). Expanded and narrow agreement between paired INR values occurred
100% of the time. Only three CoaguChek XS (5.1%) results differed by >15% compared to the
laboratory method; no results differed by more than 20% or were more than 0.5 INR units discrepant.
Conclusions: In the hands of patients the CoaguChek XS demonstrated good correlation with
laboratory determination of INR and compared very well with expanded and narrow clinical agreement
criteria. Both patients and doctors were highly satisfied with the accuracy and ease of use of the
CoaguChek XS.
Item Type: | Article |
---|---|
Authors/Creators: | Bereznicki, LRE and Jackson, SL and Peterson, GM and Jeffrey, EC and Marsden, KA and Jupe, DML |
Keywords: | warfarin, international normalised ratio, point-of-care, monitor, accuracy |
Journal or Publication Title: | Journal of Clinical Pathology |
Publisher: | BMJ Publishing Group |
ISSN: | 0021-9746 |
DOI / ID Number: | 10.1136/jcp.2006.037820 |
Additional Information: | This article has been accepted for publication in JCP following peer review. The definitive copyedited, typeset version in the Journal of Clinical Pathology 2007;60:311-314 is available online at : http://jcp.bmjjournals.com/ |
Item Statistics: | View statistics for this item |
Actions (login required)
![]() |
Item Control Page |