Open Access Repository

Widespread presence of hydrophobic paralytic shellfish toxins in Gymnodinium catenatum

Downloads

Downloads per month over past year

Negri, AP and Bolch, CJS and Geier, S and Green, DH and Park, TG and Blackburn, SI (2007) Widespread presence of hydrophobic paralytic shellfish toxins in Gymnodinium catenatum. Harmful Algae, 6 (6). pp. 774-780. ISSN 1568-9883

[img] PDF
4389.pdf | Request a copy
Full text restricted

Abstract

The toxic dinoflagellate Gymnodinium catenatum Graham produces a newly discovered sub-class of paralytic shellfish toxins (PSTs, saxitoxins) that contain a hydroxybenzoate moiety in place of the carbamoyl group (GC toxins: GC1–GC3). GC toxins bind strongly to sodium channels and their lipophilic nature may increase their potential to bioaccumulate in marine organisms. Cultures Australian G. catenatum strains were found to contain 12–63 mol% GC toxins. The GC toxins were also detected in strains from China (38 mol%), Japan (1–2 mol%), Portugal (58 mol%), Spain (36–54 mol%), and Uruguay (10–16 mol%). A cluster analysis of molar proportions of saxitoxin derivatives produced by strains showed clear clustering by country/region of origin, indicating that GC toxins may be very useful markers to identify the source of G. catenatum in the case of new outbreaks. The GC toxins dominate the toxin profiles of many G. catenatum strains, and can contribute significantly to sample toxicity, yet these toxins may easily escape detection using conventional chromatography, resulting in significant underestimates of sample toxicity. This has significant implications for shellfish monitoring and safety.

Item Type: Article
Keywords: Gymnodinium catenatum; Toxin; Saxitoxin; Paralytic; Shellfish; Poison; Dinoflagellate
Journal or Publication Title: Harmful Algae
Publisher: Elsevier Science BV
Page Range: pp. 774-780
ISSN: 1568-9883
Identification Number - DOI: 10.1016/j.hal.2007.04.001
Additional Information:

The definitive version is available at http://www.sciencedirect.com

Date Deposited: 07 Apr 2008 14:37
Last Modified: 18 Nov 2014 03:35
Item Statistics: View statistics for this item

Actions (login required)

Item Control Page Item Control Page
TOP