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Healthy aging: can clinical trials deliver?


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Bell, EJ 2008 , 'Healthy aging: can clinical trials deliver?' , Annals of the New York Academy of Sciences, vol. 1114 , pp. 137-143 , doi: 10.1196/annals.1396.006.

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The potential of a transdisciplinary research method—
Quali-Quantitative Analysis (QQA)—for delivering better evidence for
healthy aging is explored. Illustrative reviews from the literature on
healthy aging are summarized, as are papers on methodology by Charles
Ragin and colleagues. The evidence needs for healthy aging are explored,
particularly in relation to the ability of randomized controlled trials
(RCTs) to deliver rich, diversity-oriented evidence. The techniques of
QQA, which involves treating cases as configurations, are described. The
QQA method has potential value for healthy aging research in that: (a) it
could provide evidence in combinatorial forms useful to holistic practice;
(b) it could enrich the evidence for practice by providing more rigorous
information from small-N groups, within RCTs and where RCTs cannot
be used; and (c) it could add to the ability of RCTs to generate theoretical

Item Type: Article
Authors/Creators:Bell, EJ
Keywords: healthy aging • transdisciplinary research methods • randomized controlled trials • evidence for practice
Journal or Publication Title: Annals of the New York Academy of Sciences
Publisher: Blackwell Publishing
ISSN: 0077-8923
DOI / ID Number: 10.1196/annals.1396.006
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