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Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive-Compulsive Disorder and Other Anxiety Disorders

Pridmore, S, Marcolin, MA, Ribeiro, CS and Mansur, CG 2007 , 'Repetitive Transcranial Magnetic Stimulation in the Treatment of Obsessive-Compulsive Disorder and Other Anxiety Disorders' , Advances in Biological Psychiatry, vol. 23 , pp. 124-133 , doi: 10.1159/000101034.

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Abstract

Repetitive transcranial magnetic stimulation (rTMS) is being investigated as a treatment of psychiatric disorders. This chapter reviews publications of the treatment of anxiety disorders: obsessive-compulsive disorder (OCD), posttraumatic stress disorder (PTSD) and panic disorder (PD). No definite conclusions can be reached as insufficient work has been completed. Many reports are single-case or small case studies and there have been few blind studies. There is no standardization of the site of stimulation or treatment parameters. OCD: there is some early evidence that 10-Hz stimulation of the left dorsolateral prefrontal cortex and right dorsolateral prefrontal cortex, and 1-Hz simultaneous stimulation of the left and right supplementary motor area may reduce symptoms. PTSD: one blind study suggests 10-Hz stimulation of the right dorsolateral prefrontal cortex may reduce core symptoms (reexperiencing, avoidance and hyperarousal). PD: 3 case studies have been published; 1 found that 1-Hz stimulation of the right dorsolateral prefrontal cortex reduced symptoms and response to cholecystokinin tetrapeptide challenge. Further work will clarify the role (if any) of rTMS in the treatment of these 3 disorders.

Item Type: Article
Authors/Creators:Pridmore, S and Marcolin, MA and Ribeiro, CS and Mansur, CG
Journal or Publication Title: Advances in Biological Psychiatry
Publisher: S. Karger AG
ISSN: 0378-7354
DOI / ID Number: 10.1159/000101034
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