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Comparison of 6-month outcomes of COVID-19 vs Non-COVID-19 survivors of critical illness


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Hodgson, CL, Higgins, AM, Bailey, MJ, Mather, AM, Beach, L, Bellomo, R, Bissett, B, Boden, IJ ORCID: 0000-0002-9283-4779, Bradley, S, Burrell, A, Cooper, DJ, Fulcher, BJ, Haines, KJ, Hodgson, IT, Hopkins, J, Jones, AYM, Lane, S, Lawrence, D, van der Lee, L, Liacos, J, Linke, NJ, Marques Gomes, L, Nickels, M, Ntoumenopoulos, G, Myles, PS, Patman, S, Paton, M, Pound, G, Rai, S, Rix, A, Rollinson, TC, Tipping, CJ, Thomas, P, Trapani, T, Udy, AA, Whitehead, C, Anderson, S and Neto, AS 2022 , 'Comparison of 6-month outcomes of COVID-19 vs Non-COVID-19 survivors of critical illness' , American Journal of Respiratory and Critical Care Medicine , doi: 10.1164/rccm.202110-2335OC.

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Rationale: The outcomes of survivors of critical illness due to COVID-19 compared to non-COVID are yet to be established. Objective: We aimed to compare new disability at 6-months in mechanically ventilated patients admitted to Australian intensive care units (ICUs) with COVID-19 compared to non-COVID-19. Methods: We included COVID-19 and non-COVID-19 critically ill patients from two prospective observational studies. Patients were eligible if they were adult (age ≥18 years) with over 24 hours of mechanical ventilation. Measurements: Demographic, intervention and hospital outcome data were obtained from electronic medical records. Survivors were contacted by telephone for functional outcomes with trained outcome assessors using the World Health Organization Disability Assessment Schedule 2.0. Main Results: Between 6 March 2020 and 21 April 2021, 120 critically ill patients with COVID-19 and between August 2017 and January 2019, 199 critically ill patients without COVID-19 fulfilled the inclusion criteria. Patients with COVID-19 were older (62 (55-71) vs 58 (44-69), p=0.019) with a lower APACHE II (17 (13-20) vs 19 (15-23), p=0.011). While duration of ventilation was longer in patients with COVID-19 compared to without COVID-19 (12 days (5-19) vs 4.8 (2.3-8.8), p

Item Type: Article
Authors/Creators:Hodgson, CL and Higgins, AM and Bailey, MJ and Mather, AM and Beach, L and Bellomo, R and Bissett, B and Boden, IJ and Bradley, S and Burrell, A and Cooper, DJ and Fulcher, BJ and Haines, KJ and Hodgson, IT and Hopkins, J and Jones, AYM and Lane, S and Lawrence, D and van der Lee, L and Liacos, J and Linke, NJ and Marques Gomes, L and Nickels, M and Ntoumenopoulos, G and Myles, PS and Patman, S and Paton, M and Pound, G and Rai, S and Rix, A and Rollinson, TC and Tipping, CJ and Thomas, P and Trapani, T and Udy, AA and Whitehead, C and Anderson, S and Neto, AS
Keywords: COVID-19, long term outcomes, critical illness, intensive care, SARS-CoV-2, recovery
Journal or Publication Title: American Journal of Respiratory and Critical Care Medicine
Publisher: Amer Thoracic Soc
ISSN: 1073-449X
DOI / ID Number: 10.1164/rccm.202110-2335OC
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Copyright 2022 American Thoracic Society

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