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Abstract

The first natural product isolation studies of Nothofagus gunnii (Hook.f.) Oerst and Nothofagus cunninghamii (Hook.f.) Oerst have been undertaken. A previously unreported stilbene derivative, pinosylvin monoacetate, was isolated from the leaves of N. gunnii, in addition to 14 known compounds; including the flavonoids galangin, pinobanksin, catechin and quercetin; sesquiterpenoids such as, ilicol and (+)-β-costol acetate; 2,4-dihydroxy-6-methoxychalcone and pinosylvin. Four known flavonoid natural products, catechin, quercetin, ayanin, and avicularin were isolated from the leaves of N. cunninghamii. This study reveals that N. gunnii is a rich source of flavonoid, chalcone and stilbene compounds, while primarily hydroxyflavonoid compounds are found in N. cunninghamii. The isolated phytochemicals are consistent with the evolutionary relationships suggested to exist among Nothofagus species.

Item Type:	Article
Authors/Creators:	Gyeltshen, T and Jordan, GJ and Smith, JA and Bissember, AC
Keywords:	Nothofagus gunnii, Nothofagus cunninghamii, flavonoids, terpenoids, stilbenes
Journal or Publication Title:	Fitoterapia
Publisher:	Elsevier Science Bv
ISSN:	0367-326X
DOI / ID Number:	10.1016/j.fitote.2021.105088
Copyright Information:	© 2021 Elsevier B.V.
Related URLs:	Google Scholar: Jordan, GJ UTAS Profile: Jordan, GJ Google Scholar: Smith, JA UTAS Profile: Smith, JA UTAS Profile: Bissember, AC
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