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Abstract

Heart failure (HF) is now the leading cause of a first major cardiovascular event and the most common hospital discharge diagnosis in older adults. A recent cohort study by Mujaj et al included 30 000 individuals at risk for HF (mean age, 67 years), of whom 26% had a history of coronary artery disease. The analysis demonstrated an increased risk of HF in those taking aspirin (adjusted hazard ratio [HR], 1.26 [95% CI, 1.12–1.41]) but highlighted the need for evidence from randomized trials.2 ASPREE (Aspirin in Reducing Events in the Elderly (URL: https://www.clinicaltrials.gov; Unique identifier: NCT01038583) was a double-blinded, randomized, placebo-controlled trial of aspirin in healthy older subjects.

Item Type:	Article
Authors/Creators:	Zhou, Z and Nelson, M and Ernst, ME and Reid, C and McNeil, J and Tonkin, A
Keywords:	aspirin, heart failure, elderly, primary prevention
Journal or Publication Title:	Circulation: Heart Failure
Publisher:	Lippincott Williams & Wilkins
ISSN:	1941-3289
Copyright Information:	Copyright 2022 American Heart Association, Inc.
Related URLs:	Google Scholar: Nelson, M UTAS Profile: Nelson, M
Item Statistics:	View statistics for this item

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