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Global perspectives on immunization during pregnancy and priorities for future research and development: an international consensus statement

Abu-Raya, B, Maertens, K, Edwards, KM, Omer, SB, Englund, JA, Flanagan, KL, Snape, MD, Amirthalingam, G, Leuridan, E, Damme, PV, Papaevangelou, V, Launay, O, Dagan, R, Campins, M, Cavaliere, AF, Frusca, T, Guidi, S, O'Ryan, M, Heininger, U, Tan, T, Alsuwaidi, AR, Safadi, MA, Vilca, LM, Wanlapakorn, N, Madhi, SA, Giles, ML, Prymula, R, Ladhani, S, Martinon-Torres, F, Tan, L, Scambia, G, Principi, N and Esposito, S 2020 , 'Global perspectives on immunization during pregnancy and priorities for future research and development: an international consensus statement' , Frontiers in Immunology, vol. 11 , doi:

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Immunization during pregnancy has been recommended in an increasing number of countries. The aim of this strategy is to protect pregnant women and infants from severe infectious disease, morbidity and mortality and is currently limited to tetanus, inactivated influenza, and pertussis-containing vaccines. There have been recent advancements in the development of vaccines designed primarily for use in pregnant women (respiratory syncytial virus and group B Streptococcus vaccines). Although there is increasing evidence to support vaccination in pregnancy, important gaps in knowledge still exist and need to be addressed by future studies. This collaborative consensus paper provides a review of the current literature on immunization during pregnancy and highlights the gaps in knowledge and a consensus of priorities for future research initiatives, in order to optimize protection for both the mother and the infant.

Item Type: Article
Authors/Creators:Abu-Raya, B and Maertens, K and Edwards, KM and Omer, SB and Englund, JA and Flanagan, KL and Snape, MD and Amirthalingam, G and Leuridan, E and Damme, PV and Papaevangelou, V and Launay, O and Dagan, R and Campins, M and Cavaliere, AF and Frusca, T and Guidi, S and O'Ryan, M and Heininger, U and Tan, T and Alsuwaidi, AR and Safadi, MA and Vilca, LM and Wanlapakorn, N and Madhi, SA and Giles, ML and Prymula, R and Ladhani, S and Martinon-Torres, F and Tan, L and Scambia, G and Principi, N and Esposito, S
Keywords: group B Streptococcus vaccines, influenza, maternal immunization, pertussis, pregnant women, respiratory syncytial virus, tetanus
Journal or Publication Title: Frontiers in Immunology
Publisher: Frontiers Research Foundation
ISSN: 1664-3224
DOI / ID Number:
Copyright Information:

Copyright © 2020 Abu-Raya, Maertens, Edwards, Omer, Englund, Flanagan, Snape, Amirthalingam, Leuridan, Damme, Papaevangelou, Launay, Dagan, Campins, Cavaliere, Frusca, Guidi, ORyan, Heininger, Tan, Alsuwaidi, Safadi, Vilca, Wanlapakorn, Madhi, Giles, Prymula, Ladhani, Martinón-Torres, Tan, Michelin, Scambia, Principi and Esposito. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (CC BY 4.0) License ( The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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