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Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants

Bezabhe, WM ORCID: 0000-0002-3028-6949, Bereznicki, LR ORCID: 0000-0003-3974-3437, Radford, J ORCID: 0000-0002-5751-0488, Wimmer, BC ORCID: 0000-0003-3166-7126, Salahudeen, MS ORCID: 0000-0001-9131-7465, Bindoff, I ORCID: 0000-0002-8170-8339 and Peterson, GM ORCID: 0000-0002-6764-3882 2022 , 'Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants' , Expert Review of Clinical Pharmacology , pp. 1-6 , doi: 10.1080/17512433.2022.2070151.

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Abstract

Compared with warfarin, prescribing of direct-acting oral anticoagulants (DOACs) was associated with a lower risk of renal function decline per 1000 person-years: hazard ratio (HR) 0.75, 95% confidence interval (CI) 0.68-0.81, p p p p = 0.003) and risk of doubling of serum creatinine (HR 0.62, 95% CI 0.40-0.95, p = 0.030).

Item Type: Article
Authors/Creators:Bezabhe, WM and Bereznicki, LR and Radford, J and Wimmer, BC and Salahudeen, MS and Bindoff, I and Peterson, GM
Keywords: estimated glomerular filtration rate, oral anticoagulant, renal function decline, dabigatran, apixaban, rivaroxaban, warfarin
Journal or Publication Title: Expert Review of Clinical Pharmacology
Publisher: Taylor & Francis
ISSN: 1751-2433
DOI / ID Number: 10.1080/17512433.2022.2070151
Copyright Information:

Copyright 2022 Informa UK Limited, trading as Taylor & Francis Group

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