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Evidence-based recommendations for the monitoring and treatment of ankylosing spondylitis: results from the Australian 3E initiative in rheumatology

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Kain, T, Zochling, J, Taylor, Andrew, Manolios, N, Smith, MD, Reed, MD, Brown, MA and Schachna, L 2008 , 'Evidence-based recommendations for the monitoring and treatment of ankylosing spondylitis: results from the Australian 3E initiative in rheumatology' , International Journal of Rheumatic Diseases, vol. 11, no. 1 , pp. 45-49 , doi: 10.1111/j.1756-185X.2008.00329.x.

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Abstract

Aim: To develop a set of Australian recommendations for the monitoring and treatment of ankylosing spondylitis
(AS) through systematic literature review combined with the opinion of practicing rheumatologists.
Methods: A set of eight questions, four in each domain of monitoring and treatment, were formulated by
voting and the Delphi method. The results of a systematic literature review addressing each question were
presented to the 23 participants of the Australian 3E meeting. All participants were clinical rheumatologists
experienced in the daily management of AS.
Results: After three rounds of breakout sessions to discuss the findings of the literature review, a set of
recommendations was finalized after discussion and voting. The category of evidence and strength of recommendation
were determined for each proposal. The level of agreement among participants was excellent (mean
84%, range 64–100%).
Conclusions: The 12 recommendations developed from evidence and expert opinion provide guidance for
the daily management of AS patients. For most recommendations, we found a paucity of supportive evidence
in the literature highlighting the need for additional clinical studies.

Item Type: Article
Authors/Creators:Kain, T and Zochling, J and Taylor, Andrew and Manolios, N and Smith, MD and Reed, MD and Brown, MA and Schachna, L
Journal or Publication Title: International Journal of Rheumatic Diseases
ISSN: 1756-1841
DOI / ID Number: 10.1111/j.1756-185X.2008.00329.x
Additional Information:

The definitive version is available at www.blackwell-synergy.com

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