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Linkage Replication of the MYP12 Locus in Common Myopia


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Chen, CY, Stankovich, J, Scurrah, KJ, Garoufalis, P, Dirani, M, Pertile, KK, Richardson, AJ and Baird, PN 2007 , 'Linkage Replication of the MYP12 Locus in Common Myopia' , Investigative Ophthalmology and Vision Science, vol. 48, no. 10 , pp. 4433-4439 , doi: 10.1167/iovs.06-1188.

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Myopia is a common disorder with a large public
health impact. Although 12 myopia loci have been reported
and heterogeneity for high myopia loci have been demonstrated,
replication of high-myopia loci with a common myopia
phenotype has not been successful. This study reports the
successful replication of MYP12 in three large, multigenerational
families with autosomal dominant (AD) common myopia
(spherical equivalent [SphE] 0.50 D).

Item Type: Article
Authors/Creators:Chen, CY and Stankovich, J and Scurrah, KJ and Garoufalis, P and Dirani, M and Pertile, KK and Richardson, AJ and Baird, PN
Journal or Publication Title: Investigative Ophthalmology and Vision Science
ISSN: 0146-0404
DOI / ID Number: 10.1167/iovs.06-1188
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