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Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography
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Kuznetsov, MA, Nesterenko, PN, Vasiyarov, GG and Staroverov, SM 2006
, 'Sorbents with immobilized glycopeptide antibiotics for separating optical isomers by high-performance liquid chromatography'
, Applied Biochemistry and Microbiology, vol. 42, no. 6
, pp. 536-544
, doi: https://doi.org/10.1134/S0003683806060020.
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Official URL: http://dx.doi.org/10.1134/S0003683806060020
Abstract
Chiral sorbents for HPLC separation of optical isomers carrying glycopeptide antibiotics (eremomycin or its eremosaminyl aglycon, ristomycin, or vancomycin) fixed onto the surface of silica gel have been synthesized. The patterns of the retention and separation of profen isomers and their dependence on the nature of the chiral selector and the eluant composition have been studied. The sorbents were shown to be highly enantiospecific in separating the isomers of α-amino-, α-hydroxy-, and α-methylphenylcarboxylic acids (profens)
| Item Type: | Article |
|---|---|
| Authors/Creators: | Kuznetsov, MA and Nesterenko, PN and Vasiyarov, GG and Staroverov, SM |
| Journal or Publication Title: | Applied Biochemistry and Microbiology |
| ISSN: | 0003-6838 (Print) 1608-3024 (Online) |
| DOI / ID Number: | https://doi.org/10.1134/S0003683806060020 |
| Additional Information: | The original publication is available at www.springerlink.com |
| Item Statistics: | View statistics for this item |
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