Open Access Repository
The effect of season on cytokine expression in multiple sclerosis and healthy subjects
Altmetric
Download Statistics
Downloads
Downloads per month over past year
Stewart, NJ, Taylor, BV, Ponsonby, AL, Pittas, F, van der Mei, IAF, Woods, GM and Walters, EH 2007
, 'The effect of season on cytokine expression in multiple sclerosis and healthy subjects'
, Journal of Neuroimmunology, vol. 188, no. 1-2
, pp. 181-186
, doi: 10.1016/j.jneuroim.2007.06.012.
![]() |
PDF
Stewart_J_Neuri...pdf | Request a copy Full text restricted |
Official URL: htpp://dx.doi.org/10.1016/j.jneuroim.2007.06.012
Abstract
We measured the levels of IFNγ, TNFα, Il-4 and Il-10 produced by mitogen-stimulated peripheral blood mononuclear cells (PBMC) from healthy people, and those with the relapse/remitting form of multiple sclerosis. Blood was taken in summer and winter. Healthy people had a summer excess of Il-4, Il-10 and TNFα, and a winter excess of IFNγ. Untreated MS cases had a summer excess of Il-10, whereas those treated with Interferon-beta had lower levels of all cytokines, and displayed no seasonal effect.
Item Type: | Article |
---|---|
Authors/Creators: | Stewart, NJ and Taylor, BV and Ponsonby, AL and Pittas, F and van der Mei, IAF and Woods, GM and Walters, EH |
Journal or Publication Title: | Journal of Neuroimmunology |
ISSN: | 0165-5728 |
DOI / ID Number: | 10.1016/j.jneuroim.2007.06.012 |
Additional Information: | The definitive version is available at http://www.sciencedirect.com |
Item Statistics: | View statistics for this item |
Actions (login required)
![]() |
Item Control Page |