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No maternally inherited diabetes and deafness mutations in a sample of 193 Tasmanian diabetics with glaucoma

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Symons, RCA, Turakulov, R, Foote, SJ, Craig, JE, McCartney, PJ and Mackey, DA 2007 , 'No maternally inherited diabetes and deafness mutations in a sample of 193 Tasmanian diabetics with glaucoma' , Ophthalmic Genetics, vol. 28, no. 1 , pp. 39-41 , doi: 10.1080/13816810701201971.

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Abstract

We tested the hypothesis that the presence of the mitochondrial
3243 A-G mutation responsible for maternally inherited
diabetes and deafness (MIDD)1 may partly explain the association
between glaucoma and diabetes mellitus. The 3243 AG
mutation has been estimated to be responsible for 1–3% of
the non-insulin-dependent diabetes mellitus cases in Northern
Europe2 and approximately 1% in Japan.3 We tested 193 DNA
samples collected from Tasmanians with both diseases recruited
through the Glaucoma Inheritance Study in Tasmania.4 No cases
with the 3243 A-G mutation were detected.

Item Type: Article
Authors/Creators:Symons, RCA and Turakulov, R and Foote, SJ and Craig, JE and McCartney, PJ and Mackey, DA
Journal or Publication Title: Ophthalmic Genetics
ISSN: 1381-6810
DOI / ID Number: 10.1080/13816810701201971
Additional Information:

The definitive version is available online at
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