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Abstract

Tasmanian devil facial tumour disease is an infectious
cancer that threatens the largest surviving marsupial
carnivore with extinction. After emerging in 1996, it
has spread across most of the range of the species,
leading to a population decline of more than 60%. This
bizarre disease, in which the cancer cells themselves are
the infective agent, illustrates some important general
principles about disease and conservation biology, including
the threat posed by loss of genetic diversity and
the potential of pathogens with frequency-dependent
transmission to cause extinction.

Item Type:	Article
Authors/Creators:	McCallum, HI
Journal or Publication Title:	Trends in Ecology & Evolution
ISSN:	0169-5347
DOI / ID Number:	https://doi.org/10.1016/j.tree.2008.07.001
Additional Information:	The definitive version is available at http://www.sciencedirect.com
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