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Abstract

The determination of free radicals and their reaction products in biological systems is discussed, with an emphasis on the use of liquid chromatographic methods for the analysis. Free radicals formed from oxygen and its reduction products, nitric oxide, and lipid radicals are considered. Whilst reversed-phase high-performance liquid chromatography has found wide application for these analyses, ion-exclusion chromatography also has significant potential and some developments in this area are described.

Item Type:	Article
Authors/Creators:	Glod, BK and Czapski, GA and Haddad, PR
Keywords:	High-performance liquid chromatography; Ion exclusion chromatography; Reactive oxygen species; Free radicals; Nitric oxide; Malonyldialdehyde
Journal or Publication Title:	TrAC - Trends in Analytical Chemistry
ISSN:	0167-2940
DOI / ID Number:	https://doi.org/10.1016/S0165-9936(00)00018-2
Additional Information:	The definitive version is available at http://www.sciencedirect.com
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