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Abstract

The immunosuppression that follows exposure to ultraviolet
radiation (UVR) is generated by complex multistep pathways
that have been only partially elucidated. The process starts with
cutaneous chromophores and most likely ends with the
amplification of subsets of T-regulatory cells. Considerable
efforts have been made to identify the roles of Langerhans cells
and keratinocytes, located in the epidermis, and dendritic cells
and macrophages, located in the dermis, in this cascade. Less
attention, by comparison, has been paid to mast cells.

Item Type:	Article
Authors/Creators:	Norval, M and Malley, RC and Woods, GM
Journal or Publication Title:	Photodermatology, Photoimmunology & Photomedicine
ISSN:	0905-4383
DOI / ID Number:	https://doi.org/10.1111/j.1600-0781.2008.00389.x
Additional Information:	The definitive published version is available online at: http://interscience.wiley.com
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